Editorial: Has Research Informed Us on the Practical Drug Treatment of Schizophrenia?

A free download of this entire editorial, posted on March 11 by Schizophrenia Bulletin Advance Access, is available by clicking here.

John M. Davis and Stefan Leucht write in their introduction:

Has the randomized controlled trial (RCT) research over the last 56 years (since antipsychotics were discovered) informed us of the central practical questions the clinician must face on how to medicate persons with schizophrenia? In this editorial, we will consider the degree to which RCT support practice in the following areas.

1. Choice of drug and indication
2. Dose
3. Emergency treatment
4. Monitoring treatment
5. When to change drug or augment
6. Depot medication
7. Long-term changes and cost
8. Progression
9. Other considerations

Click on the image to expand it. Image courtesy of Suny Downstate Medical Center.