Showing posts with label second-generation antipsychotics. Show all posts
Showing posts with label second-generation antipsychotics. Show all posts

Monday, December 1, 2008

New drug for schizophrenia offers relief from weight gain


Posted on December 1st by 3news.co.nz:
An alternative antipsychotic drug which causes less weight gain than older treatments has been funded for those with schizophrenic disorders by New Zealand’s drug buying agency Pharmac.

Patients would be able to get the drug, amisulpride (Solian) [molecular structure illustrated], from today, which has been funded without restrictions.

Pharmac’s medical director Peter Moodie said increasing the range of treatments [for schizophrenia] had benefits for a condition that was difficult to treat.

"Over recent years some of the older antipsychotic treatments have been discontinued and so increasing the choice of medicines is an advantage," he said.

He also confirmed amisulpride was less likely to cause weight gain than other antipsychotics.

The agreement also saw injection and suppository formulations of the antinausea treatment prochlorperazine (Stemetil) becoming fully funded.

Antipsychotic drugs cost Pharmac more than $60 million a year, one of the agency’s highest expenditure groups.

Saturday, December 2, 2006

Questioning Drug Costs In Schizophrenia Treatment

From the December 1, 2006 issue of Psychiatric News:

The controversy over whether the high costs of second-generation antipsychotics (SGAs) are associated with significant benefits that justify prescribing them rather than cheaper first-generation antipsychotics (FGAs) is the subject of the cost-effectiveness analysis from the National Institute of Mental Health-sponsored CATIE (Clinical Antipsychotic Trials of Intervention Effectiveness) study, reported in the December American Journal of Psychiatry (AJP).

However, the usefulness of the report is challenged by an accompanying editorial, signed by AJP Editor in Chief Robert Freedman, M.D., and cosigned by schizophrenia and antipsychotic medication experts William Carpenter Jr., M.D., and John Davis, M.D.; and Howard Goldman, M.D., Ph.D. (an AJP associate editor), Carol Tamminga, M.D. (an AJP deputy editor), and Marshall Thomas, M.D.
Drugs studied: